Applications
Genome engineering has a wide range of applications. We have therefore divided our support items into three categories based on application group. Contact us for more information.
Tg cell lines
Cas9+ (CRISPRi/CRISPRa, Cas12, Cas13), Knock-ins (e.g. reporters, gene tags)
Mutant cell lines (non Tg)
Gene Knock-outs, Special alleles (GoF, DN, Ts), Cis-regulatory element deletions/mutations
Custom library generation
Sublibraries, Arrayed libraries
Lentivirus production
for establishing CRIPSR Tg tools, single gRNA or library preparations
Cas protein production
Cas9, nCas9 D10A, nCas9 H840A, dCas9, HiFi Cas9
CRISPR Screen Readout
Pooled KO/CRISPRi/CRISPRa, RNA Screening (Cas13)
more info
Genome editing outcomes
Pooled KO/CRISPRi/CRISPRa, RNA Screening (Cas13)
Identification of Off-targets
GUIDE-seq, CIRCLE-seq, DISCOVER-seq
more info
Validation of Genetic Models
Whole Genome Sequencing, Whole genome knock in scan (NGS)